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ITGA8 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ITGA8 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7256572

Kurzübersicht für ITGA8 Antikörper (ABIN7256572)

Target

Alle ITGA8 Antikörper anzeigen
ITGA8 (Integrin alpha-8 (ITGA8))

Reaktivität

  • 36
  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 31
  • 5
  • 4
Kaninchen

Klonalität

  • 36
  • 4
Polyklonal

Konjugat

  • 21
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ITGA8 Antikörper ist unkonjugiert

Applikation

  • 27
  • 19
  • 13
  • 7
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein of human ITGA8 (NP_003629.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    ITGA8 (Integrin alpha-8 (ITGA8))

    Andere Bezeichnung

    ITGA8

    Hintergrund

    Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

    Molekulargewicht

    Observed_MW: 117 kDa

    Calculated_MW: 117 kDa

    Gen-ID

    8516

    UniProt

    P53708
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