HSD17B8 Antikörper

Produktnummer ABIN7256494

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HSD17B8 in IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für HSD17B8 Antikörper (ABIN7256494)

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B8 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktdetails anti-HSD17B8 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human HSD17B8 (NP_055049.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HSD17B8

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Andere Bezeichnung: HSD17B8

Hintergrund: In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Gen-ID: 7923

UniProt: Q92506

Pathways: Steroid Hormone Biosynthesis