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SNX13 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SNX13 in IF. Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN7256382

Kurzübersicht für SNX13 Antikörper (ABIN7256382)

Target

Alle SNX13 Antikörper anzeigen
SNX13 (Sorting Nexin 13 (SNX13))

Reaktivität

Human, Maus

Wirt

  • 13
  • 4
Kaninchen

Klonalität

  • 15
  • 2
Polyklonal

Konjugat

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SNX13 Antikörper ist unkonjugiert

Applikation

  • 17
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein of human SNX13 (NP_055947.1).

    Isotyp

    IgG
  • Applikationshinweise

    IF 1:50-1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    SNX13 (Sorting Nexin 13 (SNX13))

    Andere Bezeichnung

    SNX13

    Hintergrund

    This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

    Gen-ID

    23161

    UniProt

    Q9Y5W8

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling
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