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COASY Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COASY in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7255964

Kurzübersicht für COASY Antikörper (ABIN7255964)

Target

Alle COASY Antikörper anzeigen
COASY (CoA Synthase (COASY))

Reaktivität

  • 27
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 22
  • 8
Kaninchen

Klonalität

  • 21
  • 9
Polyklonal

Konjugat

  • 26
  • 2
  • 1
  • 1
Dieser COASY Antikörper ist unkonjugiert

Applikation

  • 25
  • 11
  • 8
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein of human COASY (NP_079509.5).

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    COASY (CoA Synthase (COASY))

    Andere Bezeichnung

    COASY

    Hintergrund

    Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.

    Molekulargewicht

    Observed_MW: 62 kDa

    Calculated_MW: 62 kDa/65 kDa

    Gen-ID

    80347

    UniProt

    Q13057

    Pathways

    Ribonucleoside Biosynthetic Process
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