SFPQ Antikörper
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- Target Alle SFPQ Antikörper anzeigen
- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SFPQ Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human SFPQ (NP_005057.1).
- Isotyp
- IgG
- Top Product
- Discover our top product SFPQ Primärantikörper
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anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 269-361) antibody
SFPQ Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 6D7 unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 578-707) antibodySFPQ Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) antibodySFPQ Reaktivität: Human IHC, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (N-Term) antibodySFPQ Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (C-Term) antibodySFPQ Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 191-240) antibodySFPQ Reaktivität: Human, Maus, Ratte, Rind (Kuh), Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 444-493) antibodySFPQ Reaktivität: Human, Maus, Ratte, Rind (Kuh), Huhn, Pferd, Meerschweinchen, Kaninchen, Affe, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 269-362) antibodySFPQ Reaktivität: Human WB, ELISA, IHC, IF, IHC (p) Wirt: Maus Monoclonal 6D7 unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (Middle Region) antibodySFPQ Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Splicing Factor Proline/glutamine-Ric (SFPQ) (AA 499-598) antibodySFPQ Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
- Andere Bezeichnung
- SFPQ (SFPQ Produkte)
- Hintergrund
- DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45, a phosphorylated form is sequestered by THRAP3 from the pre-mRNA in resting T-cells, T-cell activation and subsequent reduced phosphorylation is proposed to lead to release from THRAP3 allowing binding to pre-mRNA splicing regulatotry elements which represses exon inclusion. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. May be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A.
- Molekulargewicht
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Observed_MW: 115 kDa
Calculated_MW: 72 kDa/76 kDa
- Gen-ID
- 6421
- UniProt
- P23246
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