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PLA2G16 Antikörper

Dieses Anti-PLA2G16-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PLA2G16 in ELISA und IHC. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7254529

Kurzübersicht für PLA2G16 Antikörper (ABIN7254529)

Target

Alle PLA2G16 Antikörper anzeigen
PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

Reaktivität

Human, Maus, Ratte

Wirt

  • 17
  • 7
  • 2
Kaninchen

Klonalität

  • 21
  • 5
Polyklonal

Konjugat

  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PLA2G16 Antikörper ist unkonjugiert

Applikation

  • 15
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Antigen affinity purification

    Immunogen

    Synthetic peptide of human PLA2G16

    Isotyp

    IgG
  • Applikationshinweise

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.1 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

    Andere Bezeichnung

    PLA2G16

    Hintergrund

    Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction. Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity). N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.

    UniProt

    P53816

    Pathways

    Inositol Metabolic Process
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