Der Kaninchen Polyklonal anti-GANAB Antikörper (ABIN7254487) detektiert spezifisch GANAB in IHC und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
GANAB
Reaktivität: Human, Maus
WB, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
IHC 1:50-1:100, ELISA 1:2000-1:5000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.72 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
GANAB
(Glucosidase, Alpha, Neutral AB (GANAB))
Andere Bezeichnung
GANAB
Hintergrund
Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.