Der Kaninchen Polyklonal Anti-CD39 Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, CD39 in Proben von Human, Maus und Ratte zu detektieren.
ENTPD1(Ectonucleoside triphosphate diphosphohydrolase 1) is also named as CD39,NTPDase 1,Ecto-ATPDase 1 and belongs to the GDA1/CD39 NTPase family. In the nervous system,it can hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.It is a noncovalent tetrameric protein and that detergent inhibition of enzymatic activity is caused by dissociation of ectoapyrase tetramers into monomers.And it is a 70- to 100- kDa protein that is heavily N-glycosylated. This protein has 6 glycosylation sites and 3 isoforms(58 kDa,59 kDa and 34 kDa) produced by alternative splicing. The soluble isoform of CD39(38-478 amino acid) locates to the extracellular part and this antibody can recognize the soluble form of CD39 (38-478aa) molecule.