NUCB2 Antikörper (AA 181-280)

Produktnummer ABIN700690

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NUCB2 in FACS, IF (cc), IF (p), IHC (fro) und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für NUCB2 Antikörper (AA 181-280) (ABIN700690)

Target: NUCB2 (NES1) (Nesfatin-1 (NES1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUCB2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NUCB2 Antikörper

Bindungsspezifität: AA 181-280

Verwendungszweck: NUCB2 Polyclonal Antibody

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nesfatin-1/Nucb2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:20-100), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-NUCB2 Antikörper (ABIN700690)

Chen, Cao, Chang, Ma, Gao, Tong, Li, Han, Yi: "Increasing hypothalamic nucleobindin 2 levels and decreasing hypothalamic inflammation in obese male mice via diet and exercise alleviate obesity-associated hypogonadism." in: Neuropeptides, Vol. 74, pp. 34-43, (2019) (PubMed).

Jia, Li, Li, Wu, Xie, Lin: "Role of nesfatin-1 in a rat model of visceral hypersensitivity." in: World journal of gastroenterology : WJG, Vol. 19, Issue 22, pp. 3487-93, (2013) (PubMed).

Details zu NUCB2

Target: NUCB2 (NES1) (Nesfatin-1 (NES1))

Andere Bezeichnung: Nesfatin-1

Hintergrund:

Synonyms: NEFA, HEL-S-19, Nucleobindin-2, DNA-binding protein NEFA, Gastric cancer antigen Zg4, Prepronesfatin, NUCB2

Background: Calcium-binding protein. May have a role in calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance (By similarity).

Gen-ID: 4925

UniProt: P80303