NUCB2 Antikörper (AA 181-280)

Produktnummer ABIN700690

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NUCB2 in FACS, IF (cc), IF (p), IHC (fro) und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für NUCB2 Antikörper (AA 181-280) (ABIN700690)

Target: NUCB2 (NES1) (Nesfatin-1 (NES1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUCB2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NUCB2 Antikörper

Bindungsspezifität: AA 181-280

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nesfatin-1/Nucb2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-NUCB2 Antikörper (ABIN700690)

Chen, Cao, Chang, Ma, Gao, Tong, Li, Han, Yi: "Increasing hypothalamic nucleobindin 2 levels and decreasing hypothalamic inflammation in obese male mice via diet and exercise alleviate obesity-associated hypogonadism." in: Neuropeptides, Vol. 74, pp. 34-43, (2019) (PubMed).

Jia, Li, Li, Wu, Xie, Lin: "Role of nesfatin-1 in a rat model of visceral hypersensitivity." in: World journal of gastroenterology : WJG, Vol. 19, Issue 22, pp. 3487-93, (2013) (PubMed).

Details zu NUCB2

Target: NUCB2 (NES1) (Nesfatin-1 (NES1))

Andere Bezeichnung: Nesfatin-1

Hintergrund:

Synonyms: NEFA, HEL-S-19, Nucleobindin-2, DNA-binding protein NEFA, Gastric cancer antigen Zg4, Prepronesfatin, NUCB2

Background: Calcium-binding protein. May have a role in calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance (By similarity).

Gen-ID: 4925

UniProt: P80303