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Syntaxin 5 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Syntaxin 5 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7252510

Kurzübersicht für Syntaxin 5 Antikörper (ABIN7252510)

Target

Alle Syntaxin 5 (STX5) Antikörper anzeigen
Syntaxin 5 (STX5)

Reaktivität

Human, Maus, Ratte

Wirt

  • 13
  • 2
  • 2
Kaninchen

Klonalität

  • 15
  • 2
Polyklonal

Konjugat

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Syntaxin 5 Antikörper ist unkonjugiert

Applikation

  • 15
  • 12
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Antigen affinity purification

    Immunogen

    Fusion protein of human STX5

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.14 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Syntaxin 5 (STX5)

    Andere Bezeichnung

    STX5

    Hintergrund

    The membrane protein syntaxin 5 (STX5) is a key component of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes that regulate cellular protein transport, vesicle docking, and membrane fusion. Syntaxin 5 protein is found as a 42 kDa ("long") protein localized to the Golgi complex and endoplasmic reticulum, and a ""short"" 35 kDa isoform localized primarily to the Golgi. Formation of the syntaxin 5 SNARE complex, which also includes proteins Sec22B, Bet1, GOSR1, GOSR2, and Ykt6, allows for regulation of ER-to-Golgi transport, intra-Golgi transport, and endosome-to-Golgi retrograde transport. Research studies indicate that the syntaxin 5 SNARE complex also plays an essential role in autophagy following autophagosome formation. Intracellular protein transport mediated by the syntaxin 5 complex is required for transport and localized activity of lysosomal proteases. The experimental reduction or deletion of syntaxin 5 complex components results in non-functional lysosomes and accumulation of autophagosomes.

    Molekulargewicht

    Observed_MW: Refer to figures

    Calculated_MW: 40 kDa

    UniProt

    Q13190

    Pathways

    Transition Metal Ion Homeostasis, Regulation of Cell Size, Synaptic Vesicle Exocytosis
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