ITM2B Antikörper
Kurzübersicht für ITM2B Antikörper (ABIN7252486)
Target
Alle ITM2B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Produktmerkmale
- Polyclonal Antibody
-
Aufreinigung
- Antigen affinity purification
-
Immunogen
- Fusion protein of human ITM2B
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000, ELISA 1:5000-1:10000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.96 mg/mL
-
Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- ITM2B (Integral Membrane Protein 2B (ITM2B))
-
Andere Bezeichnung
- ITM2B
-
Hintergrund
- Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
-
Molekulargewicht
-
Observed_MW: Refer to figures
Calculated_MW: 30 kDa
-
UniProt
- Q9Y287
Target
-