RUNX2 Antikörper
Kurzübersicht für RUNX2 Antikörper (ABIN7251304)
Target
Alle RUNX2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthesized peptide derived from the Internal region of human RUNX2.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IF 1:50-1:200, ELISA 1:20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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Andere Bezeichnung
- RUNX2
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Hintergrund
- Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.
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Molekulargewicht
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Observed_MW: 56 kDa
Calculated_MW: 57 kDa
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UniProt
- Q13950
Target
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