IRS1 Antikörper (pTyr896)
Kurzübersicht für IRS1 Antikörper (pTyr896) (ABIN7250998)
Target
Alle IRS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr896
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Produktmerkmale
- Phosphorylated antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthesized peptide derived from human IRS-1 around the phosphorylation site of Tyr896
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, ELISA 1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IRS1 (Insulin Receptor Substrate 1 (IRS1))
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Andere Bezeichnung
- IRS1
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Hintergrund
- May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
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Molekulargewicht
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Observed_MW: 180 kDa
Calculated_MW: 132 kDa
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UniProt
- P35568
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Target
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