HDAC5 Antikörper (pSer498)
Kurzübersicht für HDAC5 Antikörper (pSer498) (ABIN7250734)
Target
Alle HDAC5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- pSer498
-
Produktmerkmale
- Phosphorylated antibody
-
Aufreinigung
- Affinity purification
-
Immunogen
- Synthesized peptide derived from human HDAC5 around the phosphorylation site of Ser498
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- HDAC5 (Histone Deacetylase 5 (HDAC5))
-
Andere Bezeichnung
- HDAC5
-
Hintergrund
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
-
Molekulargewicht
-
Observed_MW: 122 kDa
Calculated_MW: 122 kDa
-
UniProt
- Q9UQL6
-
Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
Target
-