PPARD Antikörper

Produktnummer ABIN7250308

Dieses Anti-PPARD-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PPARD in IF und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für PPARD Antikörper (ABIN7250308)

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPARD Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 5F4

Produktdetails anti-PPARD Antikörper

Produktmerkmale: Monoclonal Antibody

Aufreinigung: Protein A purification

Immunogen: Recombinant Protein of PPAR Delta of PPAR Delta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-200, IF 1:100-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPARD

Target: PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))

Andere Bezeichnung: PPARD

Hintergrund: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway.

UniProt: Q03181

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation