CD1a Antikörper

Produktnummer ABIN7250218

Dieses Anti-CD1a-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD1a in IF und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für CD1a Antikörper (ABIN7250218)

Target: CD1a

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD1a Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2A5

Produktdetails anti-CD1a Antikörper

Produktmerkmale: Monoclonal Antibody

Aufreinigung: Protein A purification

Immunogen: Synthetic Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300, IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CD1a

Target: CD1a

Andere Bezeichnung: CD1A

Hintergrund: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process