BMP2 Antikörper

Produktnummer ABIN7249966

Der Maus Monoklonal Anti-BMP2-Antikörper wurde für IHC validiert. Er ist geeignet, BMP2 in Proben von Ratte zu detektieren.

Kurzübersicht für BMP2 Antikörper (ABIN7249966)

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BMP2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: 2H6D12

Produktdetails anti-BMP2 Antikörper

Produktmerkmale: Monoclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse BMP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:200-1:800

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.65 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Andere Bezeichnung: BMP2

Hintergrund: Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer, 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.

UniProt: P12643, P21274, P49001

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation