ACTN1 Antikörper

Produktnummer ABIN7249742

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ACTN1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für ACTN1 Antikörper (ABIN7249742)

Target: ACTN1 (Actinin, alpha 1 (ACTN1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACTN1 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mousealpha-actinin1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.66 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ACTN1

Target: ACTN1 (Actinin, alpha 1 (ACTN1))

Andere Bezeichnung: ACTN1

Hintergrund: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 110 kDa

Calculated_MW: 102-107 kDa

UniProt: P12814, Q7TPR4, Q9Z1P2

Pathways: Cell-Cell Junction Organization