DOK3 Antikörper
Kurzübersicht für DOK3 Antikörper (ABIN7249172)
Target
Alle DOK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Fusion protein of human DOK3
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Isotyp
- IgG
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anti-Docking Protein 3 (DOK3) (AA 128-385) antibody
DOK3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (C-Term) antibodyVerified DOK3 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (AA 1-146) antibodyDOK3 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (Internal Region) antibodyDOK3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (AA 293-321), (C-Term) antibodyDOK3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB31947 unconjugated
anti-Docking Protein 3 (DOK3) (AA 1-330) antibodyDOK3 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (Internal Region) antibodyDOK3 Reaktivität: Human, Maus WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (AA 45-310) antibodyDOK3 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (C-Term) antibodyDOK3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Docking Protein 3 (DOK3) (AA 160-409) antibodyDOK3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, ELISA 1:1000-1:5000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.4 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- DOK3 (Docking Protein 3 (DOK3))
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Andere Bezeichnung
- DOK3
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Hintergrund
- DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck, Fyn, and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function
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Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 53 kDa
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UniProt
- Q7L591
Target
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