Phospholamban Antikörper
Kurzübersicht für Phospholamban Antikörper (ABIN7248713)
Target
Alle Phospholamban (PLN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human PLN
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Isotyp
- IgG
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anti-Phospholamban (PLN) (AA 1-52) antibody
PLN Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-30) antibodyPLN Reaktivität: Human ELISA, WB, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Phospholamban (PLN) (pSer16) antibodyPLN Reaktivität: Human ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-22), (N-Term) antibodyPLN Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB44799 unconjugated
anti-Phospholamban (PLN) (pThr17) antibodyPLN Reaktivität: Human, Ratte WB, DB Wirt: Kaninchen Polyclonal RB24137 unconjugated
anti-Phospholamban (PLN) (N-Term) antibodyVerified PLN Reaktivität: Human, Ratte ELISA, WB, IHC Wirt: Ziege Polyclonal unconjugated
anti-Phospholamban (PLN) (Thr17) antibodyPLN Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-52) antibodyPLN Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-35) antibodyPLN Reaktivität: Human ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Phospholamban (PLN) (AA 1-30) antibodyPLN Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated
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Applikationshinweise
- IHC 1:50-1:100, ELISA 1:5000-1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.26 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Phospholamban (PLN)
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Andere Bezeichnung
- PLN
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Hintergrund
- The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.
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UniProt
- P26678
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Pathways
- Negative Regulation of Transporter Activity
Target
-
