HIST1H2BA Antikörper
Kurzübersicht für HIST1H2BA Antikörper (ABIN7248536)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human HIST1H2BA
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Isotyp
- IgG
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anti-Histone Cluster 1, H2ba (HIST1H2BA) (acLys126) antibody
HIST1H2BA Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Cluster 1, H2ba (HIST1H2BA) (AA 1-30), (N-Term) antibodyHIST1H2BA Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB38815 unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.98 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))
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Andere Bezeichnung
- HIST1H2BA
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Hintergrund
- The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .
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Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 14 kDa
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UniProt
- Q96A08
Target
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