Calpain 9 Antikörper

Produktnummer ABIN7248374

Produktdetails anti-Calpain 9 Antikörper

Target: Calpain 9 (CAPN9)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calpain 9 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human CAPN9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Calpain 9

Target: Calpain 9 (CAPN9)

Andere Bezeichnung: CAPN9 (CAPN9 Produkte)

Synonyme: MGC83034 antikoerper, cb545 antikoerper, zgc:92451 antikoerper, wu:fb77d06 antikoerper, CAPN9 antikoerper, GC36 antikoerper, nCL-4 antikoerper, 2200003B16Rik antikoerper, nCL4 antikoerper, Ncl-4 antikoerper, calpain 9 antikoerper, calpain 9 S homeolog antikoerper, CAPN9 antikoerper, capn9.S antikoerper, capn9 antikoerper, Capn9 antikoerper

Hintergrund: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.CAPN9 (Calpain 9) is a Protein Coding gene. Diseases associated with CAPN9 include Gastric Cancer. Among its related pathways are Degradation of the extracellular matrix and Arrhythmogenic right ventricular cardiomyopathy (ARVC). GO annotations related to this gene include calcium ion binding and calcium-dependent cysteine-type endopeptidase activity. An important paralog of this gene is CAPN3.

UniProt: O14815