ABCD1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
IHC 1:60-1:450, ELISA 1:5000-1:10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1.5 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
ABCD1
(ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))
Andere Bezeichnung
ABCD1
Hintergrund
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD),an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.