Der Kaninchen Polyklonal Anti-WNK4-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, WNK4 in Proben von Human, Maus und Ratte zu detektieren.
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
WNK4
(WNK Lysine Deficient Protein Kinase 4 (WNK4))
Andere Bezeichnung
WNK4
Hintergrund
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.