PPM1M Antikörper

Produktnummer ABIN7247633

Produktdetails anti-PPM1M Antikörper

Target: PPM1M (Protein Phosphatase 1M (PP2C Domain Containing) (PPM1M))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPM1M Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human PPM1M

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.74 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPM1M

Target: PPM1M (Protein Phosphatase 1M (PP2C Domain Containing) (PPM1M))

Andere Bezeichnung: PPM1M (PPM1M Produkte)

Synonyme: 2810423O19Rik antikoerper, AW610647 antikoerper, C77250 antikoerper, PP2Ceta antikoerper, PP2C-eta antikoerper, PP2CE antikoerper, protein phosphatase 1M antikoerper, protein phosphatase, Mg2+/Mn2+ dependent 1M antikoerper, Ppm1m antikoerper, PPM1M antikoerper

Hintergrund: PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).

UniProt: Q96MI6