PPM1M Antikörper

Produktnummer ABIN7247633

Der Kaninchen Polyklonal Anti-PPM1M-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, PPM1M in Proben von Human und Maus zu detektieren.

Kurzübersicht für PPM1M Antikörper (ABIN7247633)

Target: PPM1M (Protein Phosphatase 1M (PP2C Domain Containing) (PPM1M))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPM1M Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PPM1M Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human PPM1M

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.74 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPM1M

Target: PPM1M (Protein Phosphatase 1M (PP2C Domain Containing) (PPM1M))

Andere Bezeichnung: PPM1M

Hintergrund: PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).

UniProt: Q96MI6