DNAJA4 Antikörper

Produktnummer ABIN7247618

Dieses Anti-DNAJA4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DNAJA4 in WB, ELISA und IHC. Geeignet für Human und Maus.

Kurzübersicht für DNAJA4 Antikörper (ABIN7247618)

Target: DNAJA4 (DnaJ (Hsp40) Homolog, Subfamily A, Member 4 (DNAJA4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-DNAJA4 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human DNAJA4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DNAJA4

Target: DNAJA4 (DnaJ (Hsp40) Homolog, Subfamily A, Member 4 (DNAJA4))

Andere Bezeichnung: DNAJA4

Hintergrund: The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 45 kDa

UniProt: Q8WW22