FKBP4 Antikörper

Produktnummer ABIN7247213

Dieser Anti-FKBP4-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von FKBP4 in WB, IHC und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für FKBP4 Antikörper (ABIN7247213)

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-FKBP4 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human FKBP4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.14 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FKBP4

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Andere Bezeichnung: FKBP4

Hintergrund: FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 52 kDa

UniProt: Q02790

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway