PNRC2 Antikörper
Kurzübersicht für PNRC2 Antikörper (ABIN7246772)
Target
Alle PNRC2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Fusion protein of human PNRC2
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Isotyp
- IgG
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anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (AA 1-139) antibody
PNRC2 Reaktivität: Human ELISA, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (AA 71-120) antibodyPNRC2 Reaktivität: Human, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Affe, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (N-Term) antibodyPNRC2 Reaktivität: Human, Ratte, Kaninchen, Pferd, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (N-Term) antibodyPNRC2 Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (Middle Region) antibodyPNRC2 Reaktivität: Human, Ratte, Maus, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Hund, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (N-Term) antibodyPNRC2 Reaktivität: Human, Ratte, Maus, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Hund, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC 1:30-1:150, ELISA 1:5000-1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.54 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
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Andere Bezeichnung
- PNRC2
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Hintergrund
- Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery (PubMed:19150429). May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs (PubMed:19150429). Required for UPF1/RENT1 localization to the P-body (PubMed:19150429). Plays a role in glucocorticoid receptor-mediated mRNA degradation by interacting with the glucocorticoid receptor NR3C1 in a ligand-dependent manner when it is bound to the 5' UTR of target mRNAs and recruiting the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (PubMed:25775514). Also acts as a nuclear receptor coactivator (PubMed:11574675). May play a role in controlling the energy balance between energy storage and energy expenditure (By similarity).
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UniProt
- Q9NPJ4
Target
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