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IMPA1 Antikörper

IMPA1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7246232
  • Target Alle IMPA1 Antikörper anzeigen
    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
    Reaktivität
    • 32
    • 13
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 29
    • 3
    Kaninchen
    Klonalität
    • 30
    • 2
    Polyklonal
    Konjugat
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser IMPA1 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen affinity purification
    Immunogen
    Fusion protein of human IMPA1
    Isotyp
    IgG
    Top Product
    Discover our top product IMPA1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.9 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
    Andere Bezeichnung
    IMPA1 (IMPA1 Produkte)
    Synonyme
    zgc:100926 antikoerper, 2610002K09Rik antikoerper, 2900059K10Rik antikoerper, AI325909 antikoerper, IMP antikoerper, IMPA antikoerper, impa antikoerper, inositol monophosphatase 1 antikoerper, inositol(myo)-1(or 4)-monophosphatase 1 antikoerper, inositol (myo)-1(or 4)-monophosphatase 1 antikoerper, inositol monophosphatase antikoerper, inositol(myo)-1(or 4)-monophosphatase 1 S homeolog antikoerper, impa1 antikoerper, Impa1 antikoerper, IMPA1 antikoerper, impa1.S antikoerper
    Hintergrund
    This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.
    Molekulargewicht

    Observed_MW: Refer to figures

    Calculated_MW: 30 kDa

    UniProt
    P29218
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