MYOZ2
Reaktivität: Human
WB, IHC, ICC, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
IHC 1:40-1:200, ELISA 1:5000-1:10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1.32 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
MYOZ2
(Myozenin 2 (MYOZ2))
Andere Bezeichnung
MYOZ2
Hintergrund
MYOZ2 (Myozenin 2) is a Protein Coding gene. Diseases associated with MYOZ2 include Cardiomyopathy, Hypertrophic, 16 and Myoz2-Related Familial Hypertrophic Cardiomyopathy. GO annotations related to this gene include actin binding and telethonin binding. An important paralog of this gene is MYOZ1.The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.