PHF21A Antikörper

Produktnummer ABIN7246025

Produktdetails anti-PHF21A Antikörper

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF21A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human PHF21A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PHF21A

Target: PHF21A (PHD Finger Protein 21A (PHF21A))

Andere Bezeichnung: PHF21A (PHF21A Produkte)

Synonyme: PHF21A antikoerper, im:7138823 antikoerper, si:dkey-23n7.9 antikoerper, BHC80 antikoerper, RGD1560612 antikoerper, 80kDa antikoerper, Bhc antikoerper, Bhc80 antikoerper, D030065N23Rik antikoerper, PFTF1 antikoerper, fj98d03 antikoerper, phf21a antikoerper, wu:fj98d03 antikoerper, PHD finger protein 21A antikoerper, PHD finger protein 21Aa antikoerper, PHD finger protein 21Ab antikoerper, PHF21A antikoerper, phf21aa antikoerper, pf21a antikoerper, phf21a antikoerper, LOC100549929 antikoerper, Phf21a antikoerper, phf21ab antikoerper

Hintergrund: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 75 kDa

UniProt: Q96BD5

Pathways: Feeding Behaviour