BAIAP2L1 Antikörper

Produktnummer ABIN7246010

Dieses Anti-BAIAP2L1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BAIAP2L1 in WB, ELISA und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für BAIAP2L1 Antikörper (ABIN7246010)

Target: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAIAP2L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-BAIAP2L1 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human BAIAP2L1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BAIAP2L1

Target: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Andere Bezeichnung: BAIAP2L1

Hintergrund: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 57 kDa

UniProt: Q9UHR4

Pathways: Regulation of Actin Filament Polymerization