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BAIAP2L1 Antikörper

This anti-BAIAP2L1 antibody (ABIN7246010) is a Rabbit Polyclonal antibody detecting BAIAP2L1 in WB, ELISA, IHC. Suitable for Human, Mouse, Rat.
Produktnummer ABIN7246010

Kurzübersicht für BAIAP2L1 Antikörper (ABIN7246010)

Target

Alle BAIAP2L1 Antikörper anzeigen
BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Reaktivität

Human, Maus, Ratte

Wirt

  • 26
  • 3
Kaninchen

Klonalität

  • 26
  • 3
Polyklonal

Konjugat

  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BAIAP2L1 Antikörper ist unkonjugiert

Applikation

  • 17
  • 12
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Antigen affinity purification

    Immunogen

    Fusion protein of human BAIAP2L1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:1000-1:5000, IHC 1:30-1:150, ELISA 1:5000-1:10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.7 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

    Andere Bezeichnung

    BAIAP2L1

    Hintergrund

    This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

    Molekulargewicht

    Observed_MW: Refer to figures

    Calculated_MW: 57 kDa

    UniProt

    Q9UHR4

    Pathways

    Regulation of Actin Filament Polymerization
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