USP12 Antikörper

Produktnummer ABIN7245977

Produktdetails anti-USP12 Antikörper

Target: USP12 (Ubiquitin Specific Peptidase 12 (USP12))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Full length fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu USP12

Target: USP12 (Ubiquitin Specific Peptidase 12 (USP12))

Andere Bezeichnung: USP12 (USP12 Produkte)

Synonyme: UBH1 antikoerper, USP12L1 antikoerper, usp12 antikoerper, USP12P1 antikoerper, sb:eu882 antikoerper, wu:fi09d12 antikoerper, Ubh1 antikoerper, ubh1 antikoerper, usp12l1 antikoerper, ubiquitin specific peptidase 12 antikoerper, ubiquitin specific peptidase 12a antikoerper, ubiquitin specific peptidase 12 L homeolog antikoerper, ubiquitin specific peptidase 12 S homeolog antikoerper, USP12 antikoerper, usp12 antikoerper, Usp12 antikoerper, usp12a antikoerper, usp12.L antikoerper, usp12.S antikoerper

Hintergrund: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP12 (ubiquitin specific peptidase 12), also known as UBH1 or USP12L1, is a 370 amino acid protein belonging to the peptidase C19 family and the USP12/USP46 subfamily. Considered a deubiquitinating enzyme, it is suggested that USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have high activity. The gene encoding USP12 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4 % of the human genome.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 43 kDa

UniProt: O75317