MOBKL1A Antikörper

Produktnummer ABIN7245845

Produktdetails anti-MOBKL1A Antikörper

Target: MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MOBKL1A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Full length fusion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MOBKL1A

Target: MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))

Andere Bezeichnung: MOB1B (MOB1B Produkte)

Synonyme: MATS2 antikoerper, MOB4A antikoerper, MOBKL1A antikoerper, 1110003E08Rik antikoerper, AU015450 antikoerper, B230364F10 antikoerper, Mobkl1a antikoerper, mobkl1a antikoerper, mobkl1aa antikoerper, wu:fj65h03 antikoerper, zgc:56156 antikoerper, zgc:77872 antikoerper, MOB1B antikoerper, mob4a antikoerper, mats2 antikoerper, C2orf6 antikoerper, MOB1 antikoerper, MOBK1B antikoerper, Mob4B antikoerper, cb512 antikoerper, mobkl1ab antikoerper, sb:cb512 antikoerper, zgc:111840 antikoerper, MOB kinase activator 1B antikoerper, MOB kinase activator 1Ba antikoerper, Mps one binder kinase activator-like 1A antikoerper, mps one binder kinase activator-like 1A antikoerper, MOB kinase activator 1B L homeolog antikoerper, MOB kinase activator 1Bb antikoerper, MOB1B antikoerper, Mob1b antikoerper, mob1ba antikoerper, mol1a antikoerper, LOC100282811 antikoerper, LOC100285953 antikoerper, mob1b antikoerper, mob1b.L antikoerper, mob1bb antikoerper

Hintergrund: The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene.Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 25 kDa

UniProt: Q7L9L4