MOBKL1A Antikörper
Kurzübersicht für MOBKL1A Antikörper (ABIN7245845)
Target
Alle MOBKL1A (MOB1B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Full length fusion protein
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Isotyp
- IgG
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anti-MOB Kinase Activator 1B (MOB1B) (AA 2-216) antibody
MOB1B Reaktivität: Human ELISA, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (AA 177-206), (C-Term) antibodyMOB1B Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB12538 unconjugated
anti-MOB Kinase Activator 1B (MOB1B) antibodyMOB1B Reaktivität: Human WB, IHC Wirt: Maus Monoclonal 3G9 unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (AA 101-150) antibodyMOB1B Reaktivität: Human, Maus WB, ELISA, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (AA 120-216) antibodyMOB1B Reaktivität: Human ELISA, IF Wirt: Maus Monoclonal 2F8 unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (Center) antibodyMOB1B Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Affe WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (C-Term) antibodyMOB1B Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.8 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
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Andere Bezeichnung
- MOB1B
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Hintergrund
- The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene.Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
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Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 25 kDa
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UniProt
- Q7L9L4
Target
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