RASA1 Antikörper
Kurzübersicht für RASA1 Antikörper (ABIN7245677)
Target
Alle RASA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Fusion protein of human RASA1
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Isotyp
- IgG
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anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) antibody
RASA1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 2C12 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 381-390) antibodyRASA1 Reaktivität: Human, Ratte, Maus, Hund, Huhn, Frosch WB, IHC, IF, IP Wirt: Maus Monoclonal 13-RAS unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) antibodyRASA1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1E6 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 403-596) antibodyRASA1 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 201-500) antibodyRASA1 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 140-220) antibodyRASA1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) antibodyRASA1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (C-Term) antibodyRASA1 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 966-993), (C-Term) antibodyRASA1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB31772 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) antibodyRASA1 Reaktivität: Human IP Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC 1:30-1:150, ELISA 1:5000-1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
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Andere Bezeichnung
- RASA1
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Hintergrund
- The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
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UniProt
- P20936
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Pathways
- Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
Target
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