Der Kaninchen Polyklonal Anti-FAAP24-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, FAAP24 in Proben von Human und Maus zu detektieren.
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
FAAP24 (C19ORF40)
(Chromosome 19 Open Reading Frame 40 (C19ORF40))
Andere Bezeichnung
FAAP24
Hintergrund
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.