DNAJC8 Antikörper

Produktnummer ABIN7003473

Der Kaninchen Polyklonal anti-DNAJC8 Antikörper wird verwendet zum Nachweis von DNAJC8 in Proben von Human, Maus und Ratte. Er wurde validiert für IHC und ELISA.

Kurzübersicht für DNAJC8 Antikörper (ABIN7003473)

Target: DNAJC8 (DnaJ (Hsp40) Homolog, Subfamily C, Member 8 (DNAJC8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJC8 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-DNAJC8 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human DNAJC8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.44 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DNAJC8

Target: DNAJC8 (DnaJ (Hsp40) Homolog, Subfamily C, Member 8 (DNAJC8))

Andere Bezeichnung: DNAJC8

Hintergrund: The DnaJ family is one of the largest of all chaperone families and has evolved with diverse cellular localization and functions. Presence of a J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are derived from Escherichia coli and are under the control of the htpR regulatory protein. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. DnaJ proteins contain cysteine rich regions that are composed of zinc fingers, which form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJC8 (DnaJ (Hsp 40) homolog, subfamily C, member 8), also known as SPF31 or HSPC331, is a 253 amino acid protein that is suggested to have a potential role as a cochaperone in RNA processing-related processes.

UniProt: O75937