CARD16 Antikörper
Kurzübersicht für CARD16 Antikörper (ABIN7244684)
Target
Alle CARD16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human CARD16
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Isotyp
- IgG
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anti-Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 1-97) antibody
CARD16 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 1-97) antibodyCARD16 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 1-97) antibodyCARD16 Reaktivität: Human ELISA, WB Wirt: Maus Monoclonal 3E10 unconjugated
anti-Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 1-197) antibodyCARD16 Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 44-73), (N-Term) antibodyCARD16 Reaktivität: Human WB, FACS, EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.1 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
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Andere Bezeichnung
- CARD16
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Hintergrund
- Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
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Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 23 kDa
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UniProt
- Q5EG05
Target
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