CARD16 Antikörper
Kurzübersicht für CARD16 Antikörper (ABIN7244684)
Target
Alle CARD16 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
 - Polyclonal Antibody
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Aufreinigung
 - Antigen affinity purification
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Immunogen
 - Synthetic peptide of human CARD16
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Isotyp
 - IgG
 
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Applikationshinweise
 - WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1.1 mg/mL
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Buffer
 - PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store at -20°C. Avoid freeze / thaw cycles.
 
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- CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
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Andere Bezeichnung
 - CARD16
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Hintergrund
 - Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
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Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 23 kDa
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UniProt
 - Q5EG05
 
Target
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