CDC20B Antikörper

Produktnummer ABIN7003416

Der Kaninchen Polyklonal Anti-CDC20B-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, CDC20B in Proben von Human zu detektieren.

Kurzübersicht für CDC20B Antikörper (ABIN7003416)

Target: CDC20B (Cell Division Cycle 20B (CDC20B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC20B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CDC20B Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human CDC20B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-1:150, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CDC20B

Target: CDC20B (Cell Division Cycle 20B (CDC20B))

Andere Bezeichnung: CDC20B

Hintergrund: WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. Cdc20B (cell division cycle 20 homolog B) is a 519 amino acid protein that contains seven WD repeats and is thought to play a role in cell cycle control. Multiple isoforms of Cdc20B exist due to alternative splicing events. The gene encoding Cdc20B maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

UniProt: Q86Y33