CDC123 Antikörper

Produktnummer ABIN7244567

Produktdetails anti-CDC123 Antikörper

Target: CDC123 (Cell Division Cycle 123 Homolog (CDC123))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC123 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human CDC123

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CDC123

Target: CDC123 (Cell Division Cycle 123 Homolog (CDC123))

Andere Bezeichnung: CDC123 (CDC123 Produkte)

Synonyme: C10orf7 antikoerper, D123 antikoerper, AA959893 antikoerper, G431001I09Rik antikoerper, c10orf7 antikoerper, zgc:73119 antikoerper, MGC82051 antikoerper, MGC107806 antikoerper, cell division cycle 123 antikoerper, cell division cycle 123 homolog (S. cerevisiae) antikoerper, cell division cycle 123 S homeolog antikoerper, cell division cycle protein 123 homolog antikoerper, CDC123 antikoerper, Cdc123 antikoerper, cdc123 antikoerper, cdc123.S antikoerper, EHI_128440 antikoerper, LOC725473 antikoerper, LOC100640991 antikoerper, LOC100650190 antikoerper

Hintergrund: The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control. Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 39 kDa

UniProt: O75794