VPS4A Antikörper

Produktnummer ABIN7244423

Produktdetails anti-VPS4A Antikörper

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS4A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human VPS4A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-150, ELISA 1:2000-10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu VPS4A

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Andere Bezeichnung: VPS4A (VPS4A Produkte)

Synonyme: vsp4 antikoerper, SKD1 antikoerper, SKD1A antikoerper, SKD2 antikoerper, VPS4 antikoerper, VPS4-1 antikoerper, zgc:153907 antikoerper, 4930589C15Rik antikoerper, AI325971 antikoerper, AW553189 antikoerper, vacuolar protein sorting 4 homolog A antikoerper, vacuolar sorting protein 4 antikoerper, vacuolar protein sorting 4 homolog A L homeolog antikoerper, vacuolar protein sorting 4a homolog A (S. cerevisiae) antikoerper, vacuolar protein sorting 4A antikoerper, VPS4A antikoerper, TP03_0351 antikoerper, vps4a antikoerper, vps4a.L antikoerper, Vps4a antikoerper

Hintergrund: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18.

NCBI Accession: NP_037377

UniProt: Q9UN37

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events