UBTD2 Antikörper

Produktnummer ABIN7244369

Der Kaninchen Polyklonal anti-UBTD2 Antikörper wird verwendet zum Nachweis von UBTD2 in Proben von Human und Maus. Er wurde validiert für ELISA und IHC.

Kurzübersicht für UBTD2 Antikörper (ABIN7244369)

Target: UBTD2 (Ubiquitin Domain Containing 2 (UBTD2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBTD2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-UBTD2 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human UBTD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:30-150, ELISA 1:2000-10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.8 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UBTD2

Target: UBTD2 (Ubiquitin Domain Containing 2 (UBTD2))

Andere Bezeichnung: UBTD2

Hintergrund: UBTD2 (ubiquitin domain containing 2), also known as DCUBP (dendritic cell-derived ubiquitin-like protein), DC-UbP or SB72, is a 234 amino acid cytoplasmic and mitochondrial ubiquitin-like (UbL) protein that contains one C-terminal UbL domain. UbL proteins are involved in a variety of cellular processes, including DNA repair, protein sorting, apoptosis, protein degradation, cell division and autophagy. Predominantly expressed in dendritic cells and detected at high levels in tumor cell lines, UBTD2 has been implicated in apoptosis, cellular differentiation and tumorigenesis. The UbL domain of UBTD2 is 55 % similar and 28.6 % identical to the amino acid sequence of ubiquitin, but it lacks the Gly-Gly motif that is essential for ubiquitination. As its UbL domain does not actively ubiquitinate proteins, UBTD2 is believed to function as a shuttle factor involved in the ubiquitin system.

NCBI Accession: NP_689490

UniProt: Q8WUN7