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Necdin-Like 2 Antikörper

Dieses Anti-Necdin-Like 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Necdin-Like 2 in WB, ELISA und IHC. Geeignet für Human und Maus.
Produktnummer ABIN7242953

Kurzübersicht für Necdin-Like 2 Antikörper (ABIN7242953)

Target

Alle Necdin-Like 2 (NDNL2) Antikörper anzeigen
Necdin-Like 2 (NDNL2)

Reaktivität

  • 12
  • 11
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 11
  • 1
Kaninchen

Klonalität

  • 11
  • 1
Polyklonal

Konjugat

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Necdin-Like 2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Affinity purification

    Immunogen

    Synthetic peptide of human NDNL2

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:1000-1:5000, IHC 1:50-1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.4 mg/mL

    Buffer

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Necdin-Like 2 (NDNL2)

    Andere Bezeichnung

    NSMCE3

    Hintergrund

    The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).

    Molekulargewicht

    34 kDa

    NCBI Accession

    NP_619649

    UniProt

    Q96MG7
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