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ANO1 Antikörper

ANO1 Reaktivität: Human, Maus IHC, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7002623
  • Target Alle ANO1 Antikörper anzeigen
    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
    Reaktivität
    • 129
    • 34
    • 27
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 83
    • 50
    Kaninchen
    Klonalität
    • 68
    • 64
    • 1
    Polyklonal
    Konjugat
    • 59
    • 12
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ANO1 Antikörper ist unkonjugiert
    Applikation
    • 58
    • 50
    • 43
    • 41
    • 32
    • 20
    • 16
    • 13
    • 13
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), ELISA
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthetic peptide of human ANO1
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:200-1:1000, IHC 1:25-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
    Andere Bezeichnung
    ANO1 (ANO1 Produkte)
    Hintergrund
    TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1), is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90 % sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events.
    Molekulargewicht
    114 kDa
    NCBI Accession
    NP_060513
    UniProt
    Q5XXA6
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