Der Kaninchen Polyklonal anti-PLPP1 Antikörper wird verwendet zum Nachweis von PLPP1 in Proben von Human, Maus und Ratte. Er wurde validiert für IHC, ELISA und WB.
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
Produktmerkmale
Polyclonal Antibody
Aufreinigung
Affinity purification
Immunogen
Synthetic peptide of human PPAP2A
Isotyp
IgG
Applikationshinweise
WB 1:500-1:2000, IHC 1:25-1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
PLPP1
Hintergrund
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.