alpha Actinin 4 Antikörper
Kurzübersicht für alpha Actinin 4 Antikörper (ABIN7240841)
Target
Alle alpha Actinin 4 (ACTN4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Produktmerkmale
- Polyclonal Antibody
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant protein of human ACTN4
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.8 mg/mL
-
Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
-
Andere Bezeichnung
- ACTN4
-
Hintergrund
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.
-
Molekulargewicht
- 105 kDa
-
UniProt
- O43707
-
Pathways
- Proton Transport
Target
-