Sortilin 1 Antikörper
Kurzübersicht für Sortilin 1 Antikörper (ABIN7239479)
Target
Alle Sortilin 1 (SORT1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthetic peptide of human SORT1
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:35-1:150
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.7 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Sortilin 1 (SORT1)
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Andere Bezeichnung
- SORT1
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Hintergrund
- This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail.
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Molekulargewicht
- 92 kDa
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NCBI Accession
- NP_002950
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UniProt
- Q99523
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Pathways
- Neurotrophin Signalübertragung
Target
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